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Delirium is defined as a disturbance of consciousness and a change in cognition that develops over a short period of time.

Although various terms have been used to describe delirium (e.g.

Studies were excluded if they primarily enrolled patients with a neurological disorder or patients admitted to intensive care after cardiac surgery or organ/tissue transplantation, or centered on sedation management or alcohol or substance withdrawal.

Data were extracted on characteristics of studies, populations sampled, identification of delirium, and outcomes.

Objectives To determine the relation between delirium in critically ill patients and their outcomes in the short term (in the intensive care unit and in hospital) and after discharge from hospital.

Design Systematic review and meta-analysis of published studies.

Most of us think of a delirious patient as one who is aggressive, agitated, pulling out lines, and possibly hallucinating.

Our neonatologists and pediatric sub-specialists determine which newborn infants would benefit from the use of the cooling blankets and work with families to determine the best plan of action for their child.Data sources Pub Med, Embase, CINAHL, Cochrane Library, and Psych INFO, with no language restrictions, up to 1 January 2015.Eligibility criteria for selection studies Reports were eligible for inclusion if they were prospective observational cohorts or clinical trials of adults in intensive care units who were assessed with a validated delirium screening or rating system, and if the association was measured between delirium and at least one of four clinical endpoints (death during admission, length of stay, duration of mechanical ventilation, and any outcome after hospital discharge).Delirium outside of the ICU has been studied in more detail, and is associated with a three-fold increase in mortality, increased incidence of infection, and increased hospital stay, along with long lasting and severe cognitive impairment.It would seem reasonable to expect that delirium in the ICU would cause the same problems.Accepted for publication 3 April 2014 Published Volume 2014:9 Pages 879—885 DOI

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