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It's a mirror of every DS flashcart firmware and software file that I can get my hands on. M3 Sakura is a newer official loader for the M3 Real.
Because a large majority of these cards come from Asia, the servers the files are hosted on are slow, unreadable and unreliable for the rest of the world. I also keep a complete version archive, just in case anyone needs old versions and the developers' sites don't keep them. Co-developed by the author of Moonshell, it has a new GUI with integrated media playback functions.
If this doesn't help, either, post your question on the forums.
We put these at the top, hoping that it will cover 90% of questions and cut down noise in the forum.   For extra credit, contemplate why this might have changed. Don't waste time asking, it will only make us angry. If a game really doesn't work, no matter what you try, you can submit a bug report for the game. If you are running De Smu ME on a laptop, then a laptop cooler might help.
If you can't make it work, then give up and go buy the cart. If you create new threads in our forum about these games, don't be surprised if they get closed or deleted depending on how obnoxious they are. Uncheck display input De Smu ME is a very CPU demanding app.
Online support for certain 3DS games, multiplayers support for ALL DS games 7.
Replace game files with custom game files (Emulated NAND) 10.
You can get the package from the Essential Utilities category.